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Comparative DNA methylomic analyses reveal potential origins of novel epigenetic biomarkers of insulin resistance in monocytes from virally suppressed HIV-infected adults

BACKGROUND: Compared to healthy individuals, those with stably repressed HIV experience a higher risk of developing insulin resistance, a hallmark of pre-diabetes and a major determinant for cardiometabolic diseases. Although epigenetic processes, including in particular DNA methylation, appear to b...

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Detalles Bibliográficos
Autores principales: Dye, Christian K., Corley, Michael J., Li, Dongmei, Khadka, Vedbar S., Mitchell, Brooks I., Sultana, Razvan, Lum-Jones, Annette, Shikuma, Cecilia M., Ndhlovu, Lishomwa C., Maunakea, Alika K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599380/
https://www.ncbi.nlm.nih.gov/pubmed/31253200
http://dx.doi.org/10.1186/s13148-019-0694-1