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Improvement of Gut Microbiota by Inhibition of P38 Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway in Rats with Severe Acute Pancreatitis
BACKGROUND: Gut microbiota dysbiosis plays a key role in pathogenesis of severe acute pancreatitis (SAP). In this study, we explored the protective effects of the p38 MAPK inhibitor, SB203580, against gut inflammation and microbiota dysbiosis induced by pancreatic duct injection with 3.5% sodium tau...
Autores principales: | Wan, You-Dong, Zhu, Rui-Xue, Bian, Zhong-Zheng, Pan, Xin-Ting |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599419/ https://www.ncbi.nlm.nih.gov/pubmed/31226101 http://dx.doi.org/10.12659/MSM.914538 |
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