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Improvement of Gut Microbiota by Inhibition of P38 Mitogen-Activated Protein Kinase (MAPK) Signaling Pathway in Rats with Severe Acute Pancreatitis

BACKGROUND: Gut microbiota dysbiosis plays a key role in pathogenesis of severe acute pancreatitis (SAP). In this study, we explored the protective effects of the p38 MAPK inhibitor, SB203580, against gut inflammation and microbiota dysbiosis induced by pancreatic duct injection with 3.5% sodium tau...

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Detalles Bibliográficos
Autores principales: Wan, You-Dong, Zhu, Rui-Xue, Bian, Zhong-Zheng, Pan, Xin-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599419/
https://www.ncbi.nlm.nih.gov/pubmed/31226101
http://dx.doi.org/10.12659/MSM.914538

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