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Gene mapping and molecular analysis of hereditarynon-polyposis colorectal cancer (Lynch Syndrome)using systems biological approaches

Hereditary non-polyposis colorectal cancer (HNPCC) also known as Lynch Syndrome (LS), is a hereditary form of colorectal cancer (CRC). LSis caused by mutations in the mismatch repair (MMR) genes, mostly in MLH1, MSH2, MSH6 and PMS2. Identification of these gene mutations is essential to diagnose CRC...

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Detalles Bibliográficos
Autores principales:	Rasool, Mahmood, Karim, Sajjad, Naseer, Muhammad Imran, Pushparaj, Peter Natesan, Abuzenadah, Adel, Al-Qahtani, Mohammed Hussein
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599435/ https://www.ncbi.nlm.nih.gov/pubmed/31285644 http://dx.doi.org/10.6026/97320630015269

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