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Screening of caspase-3 inhibitors from natural molecule database using e-pharmacophore and docking studies
Caspase a protease family member, have a vital role in cell death and inflammation process. Caspase-3, an effector caspase controls the regulation of apoptosis and has an anti apoptotic function. The mechanical significance of restoring apoptosis signaling to selectively target malignant cells is ut...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Biomedical Informatics
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599438/ https://www.ncbi.nlm.nih.gov/pubmed/31285640 http://dx.doi.org/10.6026/97320630015240 |