Molecular docking analysis of netropsin and novobiocin with the viral protein targets HABD, MTD and RCD

Dengue, West Nile and Zika virus belongs to the family flaviviridae and genus flavivirus. It is of interest to design and develop inhibitors with improved activity against these diseases. We used the helicases target to screen for potential inhibitors against these viruses using molecular docking an...

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Autores principales: Alwabli, Afaf S, Alattas, Sana G, Alhebshi, Alawiah M, Zabermawi, Nidal M, Alkenani, Naser, ghmady, Khalid Al, Qadri, Ishtiaq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599439/
https://www.ncbi.nlm.nih.gov/pubmed/31285639
http://dx.doi.org/10.6026/97320630015233
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author Alwabli, Afaf S
Alattas, Sana G
Alhebshi, Alawiah M
Zabermawi, Nidal M
Alkenani, Naser
ghmady, Khalid Al
Qadri, Ishtiaq
author_facet Alwabli, Afaf S
Alattas, Sana G
Alhebshi, Alawiah M
Zabermawi, Nidal M
Alkenani, Naser
ghmady, Khalid Al
Qadri, Ishtiaq
author_sort Alwabli, Afaf S
collection PubMed
description Dengue, West Nile and Zika virus belongs to the family flaviviridae and genus flavivirus. It is of interest to design and develop inhibitors with improved activity against these diseases. We used the helicases target to screen for potential inhibitors against these viruses using molecular docking analysis. NS3 helicases of flavivirus family of viruses such as Dengue, West Nile and Zika are prime targets for drug development. The computer aided molecular docking analysis of netropsin and novobiocin with the viral protein targets HABD, MTD and RCD is reported for further consideration.
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spelling pubmed-65994392019-07-08 Molecular docking analysis of netropsin and novobiocin with the viral protein targets HABD, MTD and RCD Alwabli, Afaf S Alattas, Sana G Alhebshi, Alawiah M Zabermawi, Nidal M Alkenani, Naser ghmady, Khalid Al Qadri, Ishtiaq Bioinformation Research Article Dengue, West Nile and Zika virus belongs to the family flaviviridae and genus flavivirus. It is of interest to design and develop inhibitors with improved activity against these diseases. We used the helicases target to screen for potential inhibitors against these viruses using molecular docking analysis. NS3 helicases of flavivirus family of viruses such as Dengue, West Nile and Zika are prime targets for drug development. The computer aided molecular docking analysis of netropsin and novobiocin with the viral protein targets HABD, MTD and RCD is reported for further consideration. Biomedical Informatics 2019-03-30 /pmc/articles/PMC6599439/ /pubmed/31285639 http://dx.doi.org/10.6026/97320630015233 Text en © 2019 Biomedical Informatics http://creativecommons.org/licenses/by/3.0/ This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Alwabli, Afaf S
Alattas, Sana G
Alhebshi, Alawiah M
Zabermawi, Nidal M
Alkenani, Naser
ghmady, Khalid Al
Qadri, Ishtiaq
Molecular docking analysis of netropsin and novobiocin with the viral protein targets HABD, MTD and RCD
title Molecular docking analysis of netropsin and novobiocin with the viral protein targets HABD, MTD and RCD
title_full Molecular docking analysis of netropsin and novobiocin with the viral protein targets HABD, MTD and RCD
title_fullStr Molecular docking analysis of netropsin and novobiocin with the viral protein targets HABD, MTD and RCD
title_full_unstemmed Molecular docking analysis of netropsin and novobiocin with the viral protein targets HABD, MTD and RCD
title_short Molecular docking analysis of netropsin and novobiocin with the viral protein targets HABD, MTD and RCD
title_sort molecular docking analysis of netropsin and novobiocin with the viral protein targets habd, mtd and rcd
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599439/
https://www.ncbi.nlm.nih.gov/pubmed/31285639
http://dx.doi.org/10.6026/97320630015233
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