A comparative analysis of BCL-2 family

The BCL-2 family is conserved in evolution and shares a BCL-2 homology domain. It promotes and inhibits apoptosis. It is also known that apoptosis has a major role in effective cancer treatment. Therefore, it is of interest to document information related to the BCL-2 family of proteins for analysis...

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Detalles Bibliográficos
Autor principal: Choudhury, Shouhartha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599443/
https://www.ncbi.nlm.nih.gov/pubmed/31285648
http://dx.doi.org/10.6026/97320630015299
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author Choudhury, Shouhartha
author_facet Choudhury, Shouhartha
author_sort Choudhury, Shouhartha
collection PubMed
description The BCL-2 family is conserved in evolution and shares a BCL-2 homology domain. It promotes and inhibits apoptosis. It is also known that apoptosis has a major role in effective cancer treatment. Therefore, it is of interest to document information related to the BCL-2 family of proteins for analysis by prediction tools. Hence, insights from a prediction based comparative functional analysis of 108 genes in this family are documented.
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spelling pubmed-65994432019-07-08 A comparative analysis of BCL-2 family Choudhury, Shouhartha Bioinformation Research Article The BCL-2 family is conserved in evolution and shares a BCL-2 homology domain. It promotes and inhibits apoptosis. It is also known that apoptosis has a major role in effective cancer treatment. Therefore, it is of interest to document information related to the BCL-2 family of proteins for analysis by prediction tools. Hence, insights from a prediction based comparative functional analysis of 108 genes in this family are documented. Biomedical Informatics 2019-04-15 /pmc/articles/PMC6599443/ /pubmed/31285648 http://dx.doi.org/10.6026/97320630015299 Text en © 2019 Biomedical Informatics http://creativecommons.org/licenses/by/3.0/ This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Choudhury, Shouhartha
A comparative analysis of BCL-2 family
title A comparative analysis of BCL-2 family
title_full A comparative analysis of BCL-2 family
title_fullStr A comparative analysis of BCL-2 family
title_full_unstemmed A comparative analysis of BCL-2 family
title_short A comparative analysis of BCL-2 family
title_sort comparative analysis of bcl-2 family
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599443/
https://www.ncbi.nlm.nih.gov/pubmed/31285648
http://dx.doi.org/10.6026/97320630015299
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