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Maternal Western-style diet affects offspring islet composition and function in a non-human primate model of maternal over-nutrition

OBJECTIVE: In humans, offspring of women who are overweight or obese are more likely to develop metabolic disease later in life. Studies in lower animal species reveal that a calorically-dense maternal diet is associated with alterations in islet cell mass and function. The long-term effects of mate...

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Detalles Bibliográficos
Autores principales: Elsakr, Joseph M., Dunn, Jennifer C., Tennant, Katherine, Zhao, Sifang Kathy, Kroeten, Karly, Pasek, Raymond C., Takahashi, Diana L., Dean, Tyler A., Velez Edwards, Digna R., McCurdy, Carrie E., Aagaard, Kjersti M., Powers, Alvin C., Friedman, Jacob E., Kievit, Paul, Gannon, Maureen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599455/
https://www.ncbi.nlm.nih.gov/pubmed/31036449
http://dx.doi.org/10.1016/j.molmet.2019.03.010