Cargando…

TNFα promotes mucosal wound repair through enhanced Platelet Activating Factor Receptor signaling in the epithelium

Pathobiology of several chronic inflammatory disorders including ulcerative colitis and Crohn’s disease is related to intermittent, spontaneous injury/ulceration of mucosal surfaces. Disease morbidity has been associated with pathologic release of the pro-inflammatory cytokine Tumor Necrosis Factor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Birkl, Dorothee, Quiros, Miguel, García-Hernández, Vicky, Zhou, Dennis W., Brazil, Jennifer C., Hilgarth, Roland, Keeney, Justin, Yulis, Mark, Bruewer, Matthias, García, Andrés J., O´Leary, Monique N., Parkos, Charles A., Nusrat, Asma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599476/ https://www.ncbi.nlm.nih.gov/pubmed/30971752 http://dx.doi.org/10.1038/s41385-019-0150-8

Ejemplares similares

Intracellular Desmoglein-2 cleavage sensitizes epithelial cells to apoptosis in response to pro-inflammatory cytokines
por: Yulis, Mark, et al.
Publicado: (2018)

Epithelial CD47 is critical for mucosal repair in the murine intestine in vivo
por: Reed, Michelle, et al.
Publicado: (2019)

Maresin-2 promotes mucosal repair and has therapeutic potential when encapsulated in thermostable nanoparticles
por: Miranda, Jael, et al.
Publicado: (2023)

Neutrophil Interactions with Epithelial Expressed ICAM-1 Enhances Intestinal Mucosal Wound Healing
por: Sumagin, R, et al.
Publicado: (2016)

JAM-A signals through the Hippo pathway to regulate intestinal epithelial proliferation
por: Fan, Shuling, et al.
Publicado: (2022)

IFN-γ and TNF-α induced GBP-1 inhibits epithelial cell proliferation through suppression of β-catenin/TCF signaling
por: Capaldo, Christopher T., et al.
Publicado: (2012)

Role of JAM-A tyrosine phosphorylation in epithelial barrier dysfunction during intestinal inflammation
por: Fan, Shuling, et al.
Publicado: (2019)

Epithelial JAM-A is fundamental for intestinal wound repair in vivo
por: Fan, Shuling, et al.
Publicado: (2022)

Sialylation regulates neutrophil transepithelial migration, CD11b/CD18 activation, and intestinal mucosal inflammatory function
por: Azcutia, Veronica, et al.
Publicado: (2023)

Intestinal epithelial BLT1 promotes mucosal repair
por: Hayashi, Shusaku, et al.
Publicado: (2022)

Inflammation-induced desmoglein-2 ectodomain shedding compromises the mucosal barrier
por: Kamekura, Ryuta, et al.
Publicado: (2015)

Protein kinase CK2 is a critical regulator of epithelial homeostasis in chronic intestinal inflammation
por: Koch, Stefan, et al.
Publicado: (2012)

Desmocollin-2 promotes intestinal mucosal repair by controlling integrin-dependent cell adhesion and migration
por: Flemming, Sven, et al.
Publicado: (2020)

Synthetic Hydrogels for Human Intestinal Organoid Generation and Colonic Wound Repair
por: Cruz-Acuña, Ricardo, et al.
Publicado: (2017)

Activation of PKCβII by PMA Facilitates Enhanced Epithelial Wound Repair through Increased Cell Spreading and Migration
por: Sumagin, Ronen, et al.
Publicado: (2013)

Claudin-23 reshapes epithelial tight junction architecture to regulate barrier function
por: Raya-Sandino, Arturo, et al.
Publicado: (2023)

Proinflammatory cytokine-induced tight junction remodeling through dynamic self-assembly of claudins
por: Capaldo, Christopher T., et al.
Publicado: (2014)

IFNγ-induced suppression of β-catenin signaling: evidence for roles of Akt and 14.3.3ζ
por: Nava, Porfirio, et al.
Publicado: (2014)

Transmigrated neutrophils in the intestinal lumen engage ICAM 1 to regulate the epithelial barrier and neutrophil recruitment
por: Sumagin, Ronen, et al.
Publicado: (2013)

Finding the sweet spot: glycosylation mediated regulation of intestinal inflammation
por: Brazil, Jennifer C., et al.
Publicado: (2021)

Salivary Scavenger and Agglutinin (SALSA) Is Expressed in Mucosal Epithelial Cells and Decreased in Bronchial Epithelium of Asthmatic Horses
por: Lee, Gary Kwok Cheong, et al.
Publicado: (2019)

Loss of desmocollin-2 confers a tumorigenic phenotype to colonic epithelial cells through activation of Akt/β-catenin signaling
por: Kolegraff, Keli, et al.
Publicado: (2011)

Neutrophil expressed CD47 regulates CD11b/CD18-dependent neutrophil transepithelial migration in the intestine in vivo.
por: Azcutia, Veronica, et al.
Publicado: (2020)

Protein kinase C activation disrupts epithelial apical junctions via ROCK-II dependent stimulation of actomyosin contractility
por: Ivanov, Andrei I, et al.
Publicado: (2009)

Tight function zonula occludens-3 regulates cyclin D1–dependent cell proliferation
por: Capaldo, Christopher T., et al.
Publicado: (2011)

Intestinal Epithelium-Derived Luminally Released Extracellular Vesicles in Sepsis Exhibit the Ability to Suppress TNF-α and IL-17A Expression in Mucosal Inflammation
por: Appiah, Michael G., et al.
Publicado: (2020)

A Unique Role for Nonmuscle Myosin Heavy Chain IIA in Regulation of Epithelial Apical Junctions
por: Ivanov, Andrei I., et al.
Publicado: (2007)

Neutrophil-derived JAML Inhibits Repair of Intestinal Epithelial Injury During Acute Inflammation
por: Weber, Dominique A., et al.
Publicado: (2014)

Mucosal Prevalence and Interactions with the Epithelium Indicate Commensalism of Sutterella spp.
por: Hiippala, Kaisa, et al.
Publicado: (2016)

Epithelium-Innate Immune Cell Axis in Mucosal Responses to SIV
por: Shang, L., et al.
Publicado: (2016)

Active thrombin produced by the intestinal epithelium controls mucosal biofilms
por: Motta, Jean-Paul, et al.
Publicado: (2019)

Editorial: Immune Responses of the Mucosal Epithelium in Chronic Lung Diseases
por: Herr, Christian, et al.
Publicado: (2020)

Wound healing of the corneal epithelium: a review
por: Ghafar, Norzana Abd, et al.
Publicado: (2021)

Analyzing epithelial and endothelial kisses in Merida
por: Nusrat, Asma, et al.
Publicado: (2013)

Microtubules regulate disassembly of epithelial apical junctions
por: Ivanov, Andrei I, et al.
Publicado: (2006)

Effects of Platelet Lysate Gels Derived from Different Blood Sources on Oral Mucosal Wound Healing: An In Vitro Study
por: Ng, Sook-Luan, et al.
Publicado: (2023)

Measurement of the effective thickness of the mucosal unstirred layer in Necturus gallbladder epithelium
Publicado: (1989)

Facilitated Peptide Transport via the Mucosal Epithelium: Impact on Tolerance Induction
por: Kenngott, Elisabeth E., et al.
Publicado: (2017)

Immunoglobulin A Mucosal Immunity and Altered Respiratory Epithelium in Cystic Fibrosis
por: Gohy, Sophie, et al.
Publicado: (2021)

Regulation of intestinal epithelial intercellular adhesion and barrier function by desmosomal cadherin desmocollin-2
por: Raya-Sandino, Arturo, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_lgujpv6ch8neohheqbsvb4f8jm