Cargando…

Alcohol induced IL-17A production in Paneth cells amplifies endoplasmic reticulum stress, apoptosis and inflammasome-IL-18 activation in the proximal small intestine in mice

Gut microbial translocation contributes to alcoholic hepatitis. Using a mouse model of alcoholic hepatitis, we investigated the effects of chronic alcohol plus binge and found increased abundance of Paneth cells and IL-17A in the proximal small intestine (PSI). Alcohol increased IL-17A production an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gyongyosi, B., Cho, Y., Lowe, P., Calenda, C.D., Iracheta-Vellve, A., Satishchandran, A., Ambade, A., Szabo, G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599481/ https://www.ncbi.nlm.nih.gov/pubmed/31105269 http://dx.doi.org/10.1038/s41385-019-0170-4

Ejemplares similares

Reduced gut microbiome protects from alcohol-induced neuroinflammation and alters intestinal and brain inflammasome expression
por: Lowe, Patrick P., et al.
Publicado: (2018)

Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice
por: Lowe, Patrick P., et al.
Publicado: (2017)

Correction: Alcohol-related changes in the intestinal microbiome influence neutrophil infiltration, inflammation and steatosis in early alcoholic hepatitis in mice
por: Lowe, Patrick P., et al.
Publicado: (2017)

FXR and TGR5 Agonists Ameliorate Liver Injury, Steatosis, and Inflammation After Binge or Prolonged Alcohol Feeding in Mice
por: Iracheta‐Vellve, Arvin, et al.
Publicado: (2018)

Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations
por: Lowe, Patrick P., et al.
Publicado: (2020)

IL-17 produced by Paneth cells drives TNF-induced shock
por: Takahashi, Nozomi, et al.
Publicado: (2008)

AN ELECTRON MICROSCOPE STUDY OF MATURE AND DIFFERENTIATING PANETH CELLS IN THE RAT, ESPECIALLY OF THEIR ENDOPLASMIC RETICULUM AND LYSOSOMES
por: Behnke, O., et al.
Publicado: (1964)

Alcoholic hepatitis accelerates early hepatobiliary cancer by increasing stemness and miR-122-mediated HIF-1α activation
por: Ambade, Aditya, et al.
Publicado: (2016)

Advanced oxidation protein products induce Paneth cells defects by endoplasmic reticulum stress in Crohn's disease
por: Shi, Jie, et al.
Publicado: (2023)

Involvement of Endoplasmic Reticulum Stress in Albuminuria Induced Inflammasome Activation in Renal Proximal Tubular Cells
por: Fang, Li, et al.
Publicado: (2013)

Daphnoretin relieves IL-1β-mediated chondrocytes apoptosis via repressing endoplasmic reticulum stress and NLRP3 inflammasome
por: Zhou, Jianbo, et al.
Publicado: (2022)

Phosphorylation-dependent Regnase-1 release from endoplasmic reticulum is critical in IL-17 response
por: Tanaka, Hiroki, et al.
Publicado: (2019)

The Roles of Endoplasmic Reticulum in NLRP3 Inflammasome Activation
por: Zhou, Yang, et al.
Publicado: (2020)

Targeted Delivery of the HLA-B(∗)27-Binding Peptide into the Endoplasmic Reticulum Suppresses the IL-23/IL-17 Axis of Immune Cells in Spondylarthritis
por: Yu, Hui-Chun, et al.
Publicado: (2017)

An epithelial-immune circuit amplifies inflammasome and IL-6 responses to SARS-CoV-2
por: Barnett, Katherine C., et al.
Publicado: (2023)

Blockade of Interplay between IL-17A and Endoplasmic Reticulum Stress Attenuates LPS-Induced Lung Injury
por: Kim, So Ri, et al.
Publicado: (2015)

IL-17RA Signaling Amplifies Antibody-Induced Arthritis
por: Sadik, Christian D., et al.
Publicado: (2011)

The Role of Endoplasmic Reticulum Stress and NLRP3 Inflammasome in Liver Disorders
por: Lu, Xueqin, et al.
Publicado: (2022)

The Role of the Effects of Endoplasmic Reticulum Stress on NLRP3 Inflammasome in Diabetes
por: Lv, Shuangyu, et al.
Publicado: (2021)

Endoplasmic reticulum stress differentially modulates the IL-6 family of cytokines in murine astrocytes and macrophages
por: Sanchez, Cristina L., et al.
Publicado: (2019)

Toll-like receptor 4-mediated endoplasmic reticulum stress induces intestinal paneth cell damage in mice following CLP-induced sepsis
por: Wang, Yijie, et al.
Publicado: (2022)

An Endoplasmic Reticulum Specific Pro‐amplifier of Reactive Oxygen Species in Cancer Cells
por: Xu, Hong‐Gui, et al.
Publicado: (2021)

IL-22 receptor signaling in Paneth cells is critical for their maturation, microbiota colonization, Th17-related immune responses, and anti-Salmonella immunity
por: Gaudino, Stephen J., et al.
Publicado: (2020)

Inflammasome and IL-1β-Mediated Disorders
por: Hoffman, Hal M., et al.
Publicado: (2010)

Bacterial DNA amplifies neutrophilic inflammation in IL-17-exposed airways
por: Mues, Nastaran, et al.
Publicado: (2023)

TSLP production by dendritic cells is modulated by IL‐1β and components of the endoplasmic reticulum stress response
por: Elder, Matthew J., et al.
Publicado: (2015)

Lyn kinase represses mucus hypersecretion by regulating IL-13-induced endoplasmic reticulum stress in asthma
por: Wang, Xing, et al.
Publicado: (2016)

IL-32 induces epithelial-mesenchymal transition by triggering endoplasmic reticulum stress in A549 cells
por: Gong, Ling, et al.
Publicado: (2020)

Role of the Inflammasome, IL-1β, and IL-18 in Bacterial Infections
por: Sahoo, Manoranjan, et al.
Publicado: (2011)

Early Mucosal Sensing of SIV Infection by Paneth Cells Induces IL-1β Production and Initiates Gut Epithelial Disruption
por: Hirao, Lauren A., et al.
Publicado: (2014)

Interleukin-17A (IL-17A): A silent amplifier of COVID-19
por: Maione, Francesco, et al.
Publicado: (2021)

Endoplasmic Reticulum Stress Induces Macrophages to Produce IL-1β During Mycobacterium bovis Infection via a Positive Feedback Loop Between Mitochondrial Damage and Inflammasome Activation
por: Liao, Yi, et al.
Publicado: (2019)

Rutin and Its Combination With Inulin Attenuate Gut Dysbiosis, the Inflammatory Status and Endoplasmic Reticulum Stress in Paneth Cells of Obese Mice Induced by High-Fat Diet
por: Guo, Xiulan, et al.
Publicado: (2018)

p38 MAPK Facilitates Crosstalk Between Endoplasmic Reticulum Stress and IL-6 Release in the Intervertebral Disc
por: Krupkova, Olga, et al.
Publicado: (2018)

Endoplasmic Reticulum Stress Sensor IRE1α Enhances IL-23 Expression by Human Dendritic Cells
por: Márquez, Saioa, et al.
Publicado: (2017)

IL-33 Alleviated Brain Damage via Anti-apoptosis, Endoplasmic Reticulum Stress, and Inflammation After Epilepsy
por: Gao, Yuan, et al.
Publicado: (2020)

Paneth cells and necrotizing enterocolitis
por: Underwood, Mark A.
Publicado: (2012)

Inflammasomes and the IL-1 Family in Bone Homeostasis and Disease
por: Tseng, Hsu-Wen, et al.
Publicado: (2022)

HMGA1 amplifies Wnt signalling and expands the intestinal stem cell compartment and Paneth cell niche
por: Xian, Lingling, et al.
Publicado: (2017)

AIM2 inflammasome mediates Arsenic-induced secretion of IL-1 β and IL-18
por: Zhang, Mingfang, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_davph0a26qd2va1uo0hs1sq5un