Nuclear envelope assembly defects link mitotic errors to chromothripsis

Defects in the architecture or integrity of the nuclear envelope (NE) are associated with a variety of human diseases(1). Micronuclei, one common nuclear aberration, are an origin for chromothripsis(2), a catastrophic mutational process commonly observed in cancer(3–5). Chromothripsis occurs after m...

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Detalles Bibliográficos
Autores principales: Liu, Shiwei, Kwon, Mijung, Mannino, Mark, Yang, Nachen, Renda, Fioranna, Khodjakov, Alexey, Pellman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599625/
https://www.ncbi.nlm.nih.gov/pubmed/30232450
http://dx.doi.org/10.1038/s41586-018-0534-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599625/
https://www.ncbi.nlm.nih.gov/pubmed/30232450
http://dx.doi.org/10.1038/s41586-018-0534-z

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