Vitamin C kills thyroid cancer cells through ROS-dependent inhibition of MAPK/ERK and PI3K/AKT pathways via distinct mechanisms

Background: Vitamin C has been demonstrated to kill BRAF mutant colorectal cancer cells selectively. BRAF mutation is the most common genetic alteration in thyroid tumor development and progression; however, the antitumor efficacy of vitamin C in thyroid cancer remains to be explored. Methods: The e...

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Detalles Bibliográficos
Autores principales: Su, Xi, Shen, Zhen, Yang, Qi, Sui, Fang, Pu, Jun, Ma, Jingjing, Ma, Sharui, Yao, Demao, Ji, Meiju, Hou, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599666/
https://www.ncbi.nlm.nih.gov/pubmed/31285773
http://dx.doi.org/10.7150/thno.35219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599666/
https://www.ncbi.nlm.nih.gov/pubmed/31285773
http://dx.doi.org/10.7150/thno.35219

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