Exploration of the TRIM Fold of MuRF1 Using EPR Reveals a Canonical Antiparallel Structure and Extended COS-Box

MuRF1 (TRIM63) is a RING-type E3 ubiquitin ligase with a predicted tripartite TRIM fold. TRIM proteins rely upon the correct placement of an N-terminal RING domain, with respect to C-terminal, specific substrate-binding domains. The TRIM domain organization is orchestrated by a central helical domai...

Descripción completa

Detalles Bibliográficos
Autores principales: Stevens, Michael, Franke, Barbara, Skorupka, Katarzyna A., Cafiso, David S., Pornillos, Owen, Mayans, Olga, Norman, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599887/
https://www.ncbi.nlm.nih.gov/pubmed/31125568
http://dx.doi.org/10.1016/j.jmb.2019.05.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599887/
https://www.ncbi.nlm.nih.gov/pubmed/31125568
http://dx.doi.org/10.1016/j.jmb.2019.05.025

Ejemplares similares