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Use of Heterologous Vesiculovirus G Proteins Circumvents the Humoral Anti-envelope Immunity in Lentivector-Based In Vivo Gene Delivery

Vesicular stomatitis virus Indiana strain glycoprotein (VSVind.G) mediates broad tissue tropism and efficient cellular uptake. Lentiviral vectors (LVs) are particularly promising, as they can efficiently transduce non-dividing cells and facilitate stable genomic transgene integration; therefore, LVs...

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Detalles Bibliográficos
Autores principales: Munis, Altar M., Mattiuzzo, Giada, Bentley, Emma M., Collins, Mary K., Eyles, James E., Takeuchi, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599914/
https://www.ncbi.nlm.nih.gov/pubmed/31254925
http://dx.doi.org/10.1016/j.omtn.2019.05.010

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