A Reversible Gastric Uptake of Bone Scintigraphy in a Patient with Hypercalcemia

Hypercalcemia is a severe complication in cases of vitamin D intoxication that can result in metastatic calcification. We herein report a female case with hypercalcemia due to eldecalcitol administration associated with the increased uptake of technetium-99m hydroxymethylene diphosphonate ((99m)Tc-H...

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Detalles Bibliográficos
Autores principales: Fukasawa, Hirotaka, Ide, Saki, Kaneko, Mai, Ishibuchi, Kento, Niwa, Hiroki, Yasuda, Hideo, Furuya, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599921/
https://www.ncbi.nlm.nih.gov/pubmed/30713296
http://dx.doi.org/10.2169/internalmedicine.2115-18
Descripción
Sumario:Hypercalcemia is a severe complication in cases of vitamin D intoxication that can result in metastatic calcification. We herein report a female case with hypercalcemia due to eldecalcitol administration associated with the increased uptake of technetium-99m hydroxymethylene diphosphonate ((99m)Tc-HMDP) as the bone-scanning agent in the stomach. A histologic assessment using biopsy specimens identified metastatic calcification of the stomach. After the normalization of serum calcium levels, the gastric uptake of (99m)Tc-HMDP disappeared. This case indicates the usefulness of bone scintigraphy with (99m)Tc-HMDP to detect visceral metastatic calcification and to monitor its therapeutic effects in patients with hypercalcemia.

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