A Reversible Gastric Uptake of Bone Scintigraphy in a Patient with Hypercalcemia

Hypercalcemia is a severe complication in cases of vitamin D intoxication that can result in metastatic calcification. We herein report a female case with hypercalcemia due to eldecalcitol administration associated with the increased uptake of technetium-99m hydroxymethylene diphosphonate ((99m)Tc-H...

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Detalles Bibliográficos
Autores principales: Fukasawa, Hirotaka, Ide, Saki, Kaneko, Mai, Ishibuchi, Kento, Niwa, Hiroki, Yasuda, Hideo, Furuya, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599921/
https://www.ncbi.nlm.nih.gov/pubmed/30713296
http://dx.doi.org/10.2169/internalmedicine.2115-18
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author Fukasawa, Hirotaka
Ide, Saki
Kaneko, Mai
Ishibuchi, Kento
Niwa, Hiroki
Yasuda, Hideo
Furuya, Ryuichi
author_facet Fukasawa, Hirotaka
Ide, Saki
Kaneko, Mai
Ishibuchi, Kento
Niwa, Hiroki
Yasuda, Hideo
Furuya, Ryuichi
author_sort Fukasawa, Hirotaka
collection PubMed
description Hypercalcemia is a severe complication in cases of vitamin D intoxication that can result in metastatic calcification. We herein report a female case with hypercalcemia due to eldecalcitol administration associated with the increased uptake of technetium-99m hydroxymethylene diphosphonate ((99m)Tc-HMDP) as the bone-scanning agent in the stomach. A histologic assessment using biopsy specimens identified metastatic calcification of the stomach. After the normalization of serum calcium levels, the gastric uptake of (99m)Tc-HMDP disappeared. This case indicates the usefulness of bone scintigraphy with (99m)Tc-HMDP to detect visceral metastatic calcification and to monitor its therapeutic effects in patients with hypercalcemia.
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spelling pubmed-65999212019-07-01 A Reversible Gastric Uptake of Bone Scintigraphy in a Patient with Hypercalcemia Fukasawa, Hirotaka Ide, Saki Kaneko, Mai Ishibuchi, Kento Niwa, Hiroki Yasuda, Hideo Furuya, Ryuichi Intern Med Case Report Hypercalcemia is a severe complication in cases of vitamin D intoxication that can result in metastatic calcification. We herein report a female case with hypercalcemia due to eldecalcitol administration associated with the increased uptake of technetium-99m hydroxymethylene diphosphonate ((99m)Tc-HMDP) as the bone-scanning agent in the stomach. A histologic assessment using biopsy specimens identified metastatic calcification of the stomach. After the normalization of serum calcium levels, the gastric uptake of (99m)Tc-HMDP disappeared. This case indicates the usefulness of bone scintigraphy with (99m)Tc-HMDP to detect visceral metastatic calcification and to monitor its therapeutic effects in patients with hypercalcemia. The Japanese Society of Internal Medicine 2019-02-01 2019-06-01 /pmc/articles/PMC6599921/ /pubmed/30713296 http://dx.doi.org/10.2169/internalmedicine.2115-18 Text en Copyright © 2019 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Fukasawa, Hirotaka
Ide, Saki
Kaneko, Mai
Ishibuchi, Kento
Niwa, Hiroki
Yasuda, Hideo
Furuya, Ryuichi
A Reversible Gastric Uptake of Bone Scintigraphy in a Patient with Hypercalcemia
title A Reversible Gastric Uptake of Bone Scintigraphy in a Patient with Hypercalcemia
title_full A Reversible Gastric Uptake of Bone Scintigraphy in a Patient with Hypercalcemia
title_fullStr A Reversible Gastric Uptake of Bone Scintigraphy in a Patient with Hypercalcemia
title_full_unstemmed A Reversible Gastric Uptake of Bone Scintigraphy in a Patient with Hypercalcemia
title_short A Reversible Gastric Uptake of Bone Scintigraphy in a Patient with Hypercalcemia
title_sort reversible gastric uptake of bone scintigraphy in a patient with hypercalcemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599921/
https://www.ncbi.nlm.nih.gov/pubmed/30713296
http://dx.doi.org/10.2169/internalmedicine.2115-18
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