Cargando…
Bacterial pathogens under high-tension: Staphylococcus aureus adhesion to von Willebrand factor is activated by force
Attachment of Staphylococcus aureus to platelets and endothelial cells involves binding of bacterial cell surface protein A (SpA) to the large plasma glycoprotein von Willebrand factor (vWF). SpA-mediated bacterial adhesion to vWF is controlled by fluid shear stress, yet little is currently known ab...
Autores principales: | Viela, Felipe, Speziale, Pietro, Pietrocola, Giampiero, Dufrêne, Yves F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shared Science Publishers OG
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600117/ https://www.ncbi.nlm.nih.gov/pubmed/31294044 http://dx.doi.org/10.15698/mic2019.07.684 |
Ejemplares similares
-
Binding of Staphylococcus aureus Protein A to von Willebrand Factor Is Regulated by Mechanical Force
por: Viela, Felipe, et al.
Publicado: (2019) -
Nanonewton forces between Staphylococcus aureus surface protein IsdB and vitronectin
por: Mathelié-Guinlet, Marion, et al.
Publicado: (2020) -
Force-clamp spectroscopy identifies a catch bond mechanism in a Gram-positive pathogen
por: Mathelié-Guinlet, Marion, et al.
Publicado: (2020) -
The Molecular Complex between Staphylococcal Adhesin SpsD and Fibronectin Sustains Mechanical Forces in the Nanonewton Range
por: Viela, Felipe, et al.
Publicado: (2020) -
Staphylococcus aureus vWF-binding protein triggers a strong interaction between clumping factor A and host vWF
por: Viljoen, Albertus, et al.
Publicado: (2021)