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The Role of Ubiquitination in Regulating Embryonic Stem Cell Maintenance and Cancer Development
Ubiquitination regulates nearly every aspect of cellular events in eukaryotes. It modifies intracellular proteins with 76-amino acid polypeptide ubiquitin (Ub) and destines them for proteolysis or activity alteration. Ubiquitination is generally achieved by a tri-enzyme machinery involving ubiquitin...
Autores principales: | Wang, Dian, Bu, Fan, Zhang, Weiwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600158/ https://www.ncbi.nlm.nih.gov/pubmed/31151253 http://dx.doi.org/10.3390/ijms20112667 |
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