Cargando…

Single-Cell Virus Sequencing of Influenza Infections That Trigger Innate Immunity

Influenza virus-infected cells vary widely in their expression of viral genes and only occasionally activate innate immunity. Here, we develop a new method to assess how the genetic variation in viral populations contributes to this heterogeneity. We do this by determining the transcriptome and full...

Descripción completa

Detalles Bibliográficos
Autores principales:	Russell, Alistair B., Elshina, Elizaveta, Kowalsky, Jacob R., te Velthuis, Aartjan J. W., Bloom, Jesse D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Genetic Diversity and Evolution
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600203/ https://www.ncbi.nlm.nih.gov/pubmed/31068418 http://dx.doi.org/10.1128/JVI.00500-19

Ejemplares similares

The influenza virus RNA polymerase as an innate immune agonist and antagonist
por: Elshina, Elizaveta, et al.
Publicado: (2021)

Deep Mutational Scan of the Highly Conserved Influenza A Virus M1 Matrix Protein Reveals Substantial Intrinsic Mutational Tolerance
por: Hom, Nancy, et al.
Publicado: (2019)

The effect of single mutations in Zika virus envelope on escape from broadly neutralizing antibodies
por: Kikawa, Caroline, et al.
Publicado: (2023)

Transmission Bottleneck Size Estimation from Pathogen Deep-Sequencing Data, with an Application to Human Influenza A Virus
por: Sobel Leonard, Ashley, et al.
Publicado: (2017)

Complete Genome Sequencing of Influenza A Viruses within Swine Farrow-to-Wean Farms Reveals the Emergence, Persistence, and Subsidence of Diverse Viral Genotypes
por: Diaz, Andres, et al.
Publicado: (2017)

Deep Sequencing of Influenza A Virus from a Human Challenge Study Reveals a Selective Bottleneck and Only Limited Intrahost Genetic Diversification
por: Sobel Leonard, Ashley, et al.
Publicado: (2016)

Single-Genome Sequencing of Hepatitis C Virus in Donor-Recipient Pairs Distinguishes Modes and Models of Virus Transmission and Early Diversification
por: Li, Hui, et al.
Publicado: (2015)

Immune Escape Adaptive Mutations in Hemagglutinin Are Responsible for the Antigenic Drift of Eurasian Avian-Like H1N1 Swine Influenza Viruses
por: Xu, Chengzhi, et al.
Publicado: (2022)

Evidence for the Introduction, Reassortment, and Persistence of Diverse Influenza A Viruses in Antarctica
por: Hurt, Aeron C., et al.
Publicado: (2016)

Genetic Characterization of Influenza A Viruses in Japanese Swine in 2015 to 2019
por: Mine, Junki, et al.
Publicado: (2020)

Immune Escape Adaptive Mutations in the H7N9 Avian Influenza Hemagglutinin Protein Increase Virus Replication Fitness and Decrease Pandemic Potential
por: Chang, Pengxiang, et al.
Publicado: (2020)

Avian Influenza Viruses in Wild Birds: Virus Evolution in a Multihost Ecosystem
por: Venkatesh, Divya, et al.
Publicado: (2018)

Molecular Characterization of Influenza C Viruses from Outbreaks in Hong Kong SAR, China
por: Daniels, Rodney S., et al.
Publicado: (2020)

Molecular Epidemiology and Evolution of Influenza Viruses Circulating within European Swine between 2009 and 2013
por: Watson, Simon J., et al.
Publicado: (2015)

Phylogeography and Antigenic Diversity of Low-Pathogenic Avian Influenza H13 and H16 Viruses
por: Verhagen, Josanne H., et al.
Publicado: (2020)

Temporal and Gene Reassortment Analysis of Influenza C Virus Outbreaks in Hong Kong, SAR, China
por: Daniels, Rodney S., et al.
Publicado: (2022)

Emergence, Evolution, and Pathogenicity of Influenza A(H7N4) Virus in Shorebirds in China
por: Chai, Hongliang, et al.
Publicado: (2022)

Characterization of Clade 7.2 H5 Avian Influenza Viruses That Continue To Circulate in Chickens in China
por: Liu, Liling, et al.
Publicado: (2016)

A Novel Type of Influenza A Virus-Derived Defective Interfering Particle with Nucleotide Substitutions in Its Genome
por: Kupke, Sascha Young, et al.
Publicado: (2019)

The Origin of Internal Genes Contributes to the Replication and Transmission Fitness of H7N9 Avian Influenza Virus
por: James, Joe, et al.
Publicado: (2022)

Genetics, Receptor Binding, Replication, and Mammalian Transmission of H4 Avian Influenza Viruses Isolated from Live Poultry Markets in China
por: Liang, Libin, et al.
Publicado: (2016)

Amino Acid Residue 217 in the Hemagglutinin Glycoprotein Is a Key Mediator of Avian Influenza H7N9 Virus Antigenicity
por: Chang, Pengxiang, et al.
Publicado: (2018)

Semi-continuous Propagation of Influenza A Virus and Its Defective Interfering Particles: Analyzing the Dynamic Competition To Select Candidates for Antiviral Therapy
por: Pelz, Lars, et al.
Publicado: (2021)

Antigenic mapping of the hemagglutinin of the H9 subtype influenza A viruses using sera from Japanese quail (Coturnix c. japonica)
por: Carnaccini, Silvia, et al.
Publicado: (2023)

Accumulation of Human-Adapting Mutations during Circulation of A(H1N1)pdm09 Influenza Virus in Humans in the United Kingdom
por: Elderfield, Ruth A., et al.
Publicado: (2014)

Genetic and Antigenic Characterization of an Influenza A(H3N2) Outbreak in Cambodia and the Greater Mekong Subregion during the COVID-19 Pandemic, 2020
por: Siegers, Jurre Y., et al.
Publicado: (2021)

Identification of Key Amino Acids in the PB2 and M1 Proteins of H7N9 Influenza Virus That Affect Its Transmission in Guinea Pigs
por: Kong, Huihui, et al.
Publicado: (2019)

Whole-Genome Sequencing and Variant Analysis of Human Papillomavirus 16 Infections
por: van der Weele, Pascal, et al.
Publicado: (2017)

Nucleic and Amino Acid Sequences Support Structure-Based Viral Classification
por: Sinclair, Robert M., et al.
Publicado: (2017)

Isolation and Characterization of the First Freshwater Cyanophage Infecting Pseudanabaena
por: Zhang, Dong, et al.
Publicado: (2020)

Corrected and Republished from: “Isolation and Characterization of the First Freshwater Cyanophage Infecting Pseudanabaena”
por: Zhang, Dong, et al.
Publicado: (2023)

Deep Sequencing of Norovirus Genomes Defines Evolutionary Patterns in an Urban Tropical Setting
por: Cotten, Matthew, et al.
Publicado: (2014)

Low-Bias RNA Sequencing of the HIV-2 Genome from Blood Plasma
por: James, Katherine L., et al.
Publicado: (2018)

Koala Retrovirus in Northern Australia Shows a Mixture of Stable Endogenization and Exogenous Lineage Diversification within Fragmented Koala Populations
por: Quigley, Bonnie L., et al.
Publicado: (2021)

Sequence Variation of Epstein-Barr Virus: Viral Types, Geography, Codon Usage, and Diseases
por: Correia, Samantha, et al.
Publicado: (2018)

Local Evolutionary Patterns of Human Respiratory Syncytial Virus Derived from Whole-Genome Sequencing
por: Agoti, Charles N., et al.
Publicado: (2015)

Spatial-Temporal Patterns of Viral Amplification and Interference Initiated by a Single Infected Cell
por: Akpinar, Fulya, et al.
Publicado: (2016)

Coinfection of Chickens with H9N2 and H7N9 Avian Influenza Viruses Leads to Emergence of Reassortant H9N9 Virus with Increased Fitness for Poultry and a Zoonotic Potential
por: Bhat, Sushant, et al.
Publicado: (2022)

Sensitive Next-Generation Sequencing Method Reveals Deep Genetic Diversity of HIV-1 in the Democratic Republic of the Congo
por: Rodgers, Mary A., et al.
Publicado: (2017)

Time-Sampled Population Sequencing Reveals the Interplay of Selection and Genetic Drift in Experimental Evolution of Potato Virus Y
por: Kutnjak, Denis, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_pk8jram73e48tunasdbtiq13cd