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Akt Signaling in Macrophage Polarization, Survival, and Atherosclerosis

The PI3K/Akt pathway plays a crucial role in the survival, proliferation, and migration of macrophages, which may impact the development of atherosclerosis. Changes in Akt isoforms or modulation of the Akt activity levels in macrophages significantly affect their polarization phenotype and consequen...

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Detalles Bibliográficos
Autores principales: Linton, MacRae F., Moslehi, Javid J., Babaev, Vladimir R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600269/
https://www.ncbi.nlm.nih.gov/pubmed/31159424
http://dx.doi.org/10.3390/ijms20112703