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Akt Signaling in Macrophage Polarization, Survival, and Atherosclerosis
The PI3K/Akt pathway plays a crucial role in the survival, proliferation, and migration of macrophages, which may impact the development of atherosclerosis. Changes in Akt isoforms or modulation of the Akt activity levels in macrophages significantly affect their polarization phenotype and consequen...
Autores principales: | Linton, MacRae F., Moslehi, Javid J., Babaev, Vladimir R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600269/ https://www.ncbi.nlm.nih.gov/pubmed/31159424 http://dx.doi.org/10.3390/ijms20112703 |
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