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IFN-γ and TNF-α aggravate endothelial damage caused by CD123-targeted CAR T cell

Background: CD123-targeted chimeric antigen receptor (CAR) T cell (CART123) for the treatment of acute myeloid leukemia (AML) and blastic plasmacytoid dendritic cell neoplasm has exhibited potential in clinical trials. However, capillary leakage syndrome, which is associated with endothelial cells d...

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Detalles Bibliográficos
Autores principales:	Sun, Yao, Wang, Shenyu, Zhao, Long, Zhang, Bin, Chen, Hu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600319/ https://www.ncbi.nlm.nih.gov/pubmed/31417286 http://dx.doi.org/10.2147/OTT.S205678

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