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Increased FLYWCH1 Expression is Negatively Correlated with Wnt/β-catenin Target Gene Expression in Acute Myeloid Leukemia Cells

Acute myeloid leukaemia (AML) is a heterogeneous clonal malignancy of hematopoietic progenitor cells. The Wnt pathway and its downstream targets are tightly regulated by β-catenin. We recently discovered a new protein, FLYWCH1, which can directly bind nuclear β-catenin. Herein, we studied the FLYWCH...

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Detalles Bibliográficos
Autores principales:	Almars, Amany, Chondrou, Panagiota S., Onyido, Emenike K., Almozyan, Sheema, Seedhouse, Claire, Babaei-Jadidi, Roya, Nateri, Abdolrahman S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600431/ https://www.ncbi.nlm.nih.gov/pubmed/31167387 http://dx.doi.org/10.3390/ijms20112739

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