Design, Synthesis and Biological Evaluation of a New Series of 1-Aryl-3-{4-[(pyridin-2-ylmethyl)thio]phenyl}urea Derivatives as Antiproliferative Agents

To discover new antiproliferative agents with high efficacy and selectivity, a new series of 1-aryl-3-{4-[(pyridin-2-ylmethyl)thio]phenyl}urea derivatives (7a–7t) were designed, synthesized and evaluated for their antiproliferative activity against A549, HCT-116 and PC-3 cancer cell lines in vitro....

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Detalles Bibliográficos
Autores principales: Zhang, Chuanming, Tan, Xiaoyu, Feng, Jian, Ding, Ning, Li, Yongpeng, Jin, Zhe, Meng, Qingguo, Liu, Xiaoping, Hu, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600452/
https://www.ncbi.nlm.nih.gov/pubmed/31167363
http://dx.doi.org/10.3390/molecules24112108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600452/
https://www.ncbi.nlm.nih.gov/pubmed/31167363
http://dx.doi.org/10.3390/molecules24112108

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