Cargando…

Structural Modifications of Nature-Inspired Indoloquinolines: A Mini Review of Their Potential Antiproliferative Activity

Cryptolepine, neocryptolepine and isocryptolepine are naturally occurring indoloquinoline alkaloids with various spectrum of biological properties. Structural modification is an extremely effective means to improve their bioactivities. This review enumerates several neocryptolepine and isocryptolepi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Ning, Świtalska, Marta, Wang, Li, Shaban, Elkhabiry, Hossain, Md Imran, El Sayed, Ibrahim El Tantawy, Wietrzyk, Joanna, Inokuchi, Tsutomu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600460/ https://www.ncbi.nlm.nih.gov/pubmed/31195640 http://dx.doi.org/10.3390/molecules24112121

Ejemplares similares

Design, Synthesis, and Biological Evaluation of Artemisinin-Indoloquinoline Hybrids as Potent Antiproliferative Agents
por: Wang, Li, et al.
Publicado: (2014)

Synthesis and In Vitro Antiproliferative Activity of 11-Substituted Neocryptolepines with a Branched ω-Aminoalkylamino Chain
por: Shaban, Elkhabiry, et al.
Publicado: (2017)

Impact of Synthesized Indoloquinoline Analog to Isolates from Cryptolepis sanguinolenta on Tumor Growth Inhibition and Hepatotoxicity in Ehrlich Solid Tumor-Bearing Female Mice
por: Nofal, Amany E., et al.
Publicado: (2023)

Isoprenoid-phospholipid conjugates as potential therapeutic agents: Synthesis, characterization and antiproliferative studies
por: Gliszczyńska, Anna, et al.
Publicado: (2017)

Synthesis and biological evaluation of phosphatidylcholines with cinnamic and 3-methoxycinnamic acids with potent antiproliferative activity
por: Czarnecka, Marta, et al.
Publicado: (2018)

Spectrofluorimetric and Computational Investigation of New Phthalimide Derivatives towards Human Neutrophil Elastase Inhibition and Antiproliferative Activity
por: Donarska, Beata, et al.
Publicado: (2022)

Synthesis and Biological Evaluation of Novel Phosphatidylcholine Analogues Containing Monoterpene Acids as Potent Antiproliferative Agents
por: Gliszczyńska, Anna, et al.
Publicado: (2016)

The N’-Substituted Derivatives of 5-Chloro-3-Methylisothiazole-4-Carboxylic Acid Hydrazide with Antiproliferative Activity
por: Jęśkowiak, Izabela, et al.
Publicado: (2019)

Indoloquinoline Ligands Favor Intercalation at Quadruplex‐Duplex Interfaces
por: Vianney, Yoanes Maria, et al.
Publicado: (2022)

Cryptolepine, an indoloquinoline alkaloid, in the management of diabetes mellitus and its associated complications
por: Ameyaw, Elvis Ofori, et al.
Publicado: (2016)

Synthesis of Indoloquinolines: An Intramolecular Cyclization Leading to Advanced Perophoramidine-Relevant Intermediates
por: Johnston, Craig A., et al.
Publicado: (2021)

Synergy between Indoloquinolines and Ciprofloxacin: An Antibiofilm Strategy against Pseudomonas aeruginosa
por: Charpentier, Emilie, et al.
Publicado: (2021)

Discovery of New 3,3-Diethylazetidine-2,4-dione Based Thiazoles as Nanomolar Human Neutrophil Elastase Inhibitors with Broad-Spectrum Antiproliferative Activity
por: Donarska, Beata, et al.
Publicado: (2022)

Synthesis, molecular docking, ctDNA interaction, DFT calculation and evaluation of antiproliferative and anti-Toxoplasma gondii activities of 2,4-diaminotriazine-thiazole derivatives
por: Łączkowski, Krzysztof Z., et al.
Publicado: (2018)

Quadruplex–Duplex Junction: A High‐Affinity Binding Site for Indoloquinoline Ligands
por: Vianney, Yoanes Maria, et al.
Publicado: (2020)

Isolation and synthesis of cryptosanguinolentine (isocryptolepine), a naturally-occurring bioactive indoloquinoline alkaloid
por: Thobokholt, Elida N., et al.
Publicado: (2020)

Design, Synthesis, and Antiproliferative Activity of Novel Neocryptolepine–Rhodanine Hybrids
por: El-Bahnsawye, Mohamed, et al.
Publicado: (2022)

Synthesis and Antiproliferative Activity of Triazoles Based on 2-Azabicycloalkanes
por: Steppeler, Franz, et al.
Publicado: (2021)

Convenient and Efficient Microwave-Assisted Synthesis of a Methyl Derivative of the Fused Indoloquinoline Alkaloid Cryptosanguinolentine
por: Gengan, Robert M., et al.
Publicado: (2010)

Indoloquinoline-Mediated Targeted Downregulation of KRAS through Selective Stabilization of the Mid-Promoter G-Quadruplex Structure
por: Psaras, Alexandra Maria, et al.
Publicado: (2022)

Synthesis, Characterization, and In Vitro Cancer Cell Growth Inhibition Evaluation of Novel Phosphatidylcholines with Anisic and Veratric Acids
por: Czarnecka, Marta, et al.
Publicado: (2018)

Highly Cancer Selective Antiproliferative Activity of Natural Prenylated Flavonoids
por: Bartmańska, Agnieszka, et al.
Publicado: (2018)

Synthesis and Antiproliferative Screening Of Novel Analogs of Regioselectively Demethylated Colchicine and Thiocolchicine
por: Czerwonka, Dominika, et al.
Publicado: (2020)

Biaryl Sulfonamides Based on the 2-Azabicycloalkane Skeleton—Synthesis and Antiproliferative Activity
por: Iwan, Dominika, et al.
Publicado: (2020)

Synthesis of Bisphenol Neolignans Inspired by Honokiol as Antiproliferative Agents
por: Cardullo, Nunzio, et al.
Publicado: (2020)

Vitamin D Analogs Potentiate the Antitumor Effect of Imatinib Mesylate in a Human A549 Lung Tumor Model
por: Maj, Ewa, et al.
Publicado: (2015)

Synthesis and in vitro antiproliferative activity of novel (4-chloro- and 4-acyloxy-2-butynyl)thioquinolines
por: Boryczka, Stanisław, et al.
Publicado: (2010)

Synthesis of novel phytol-derived γ-butyrolactones and evaluation of their biological activity
por: Gliszczyńska, Anna, et al.
Publicado: (2021)

Clopidogrel in a combined therapy with anticancer drugs—effect on tumor growth, metastasis, and treatment toxicity: Studies in animal models
por: Denslow, Agnieszka, et al.
Publicado: (2017)

Antiproliferative Activity and Molecular Docking of Novel Double-Modified Colchicine Derivatives
por: Majcher, Urszula, et al.
Publicado: (2018)

Antiproliferative Activity and in Vivo Toxicity of Double-Point Modified Analogs of 1,25-Dihydroxyergocalciferol
por: Trynda, Justyna, et al.
Publicado: (2015)

Synthesis and Antiproliferative Activity of Minor Hops Prenylflavonoids and New Insights on Prenyl Group Cyclization
por: Popłoński, Jarosław, et al.
Publicado: (2018)

Organotin Compound Derived from 3-Hydroxy-2-formylpyridine Semicarbazone: Synthesis, Crystal Structure, and Antiproliferative Activity
por: Wiecek, Joanna, et al.
Publicado: (2010)

In Vitro and In Vivo Antitumor Activity of Indolo[2,3-b] Quinolines, Natural Product Analogs from Neocryptolepine Alkaloid
por: Altwaijry, Najla, et al.
Publicado: (2021)

In Vitro Antiproliferative Evaluation of Synthetic Meroterpenes Inspired by Marine Natural Products
por: Imperatore, Concetta, et al.
Publicado: (2019)

Synthesis, Characterization, and Antiproliferative Properties of New Bio-Inspired Xanthylium Derivatives
por: Koch, Claudia, et al.
Publicado: (2023)

Synthesis, Characterization and Antiproliferative Activity of the Co(II), Ni(II), Cu(II), Pd(II) and Pt(II) Complexes of 2-(4-Thiazolyl)Benzimidazole (Thiabendazole)
por: Wisniewski, Marek Z., et al.
Publicado: (2001)

Synthesis and Antiproliferative Activities of Conjugates of Paclitaxel and Camptothecin with a Cyclic Cell-Penetrating Peptide
por: El-Sayed, Naglaa Salem, et al.
Publicado: (2019)

An efficient synthesis of indolo[2,3-b]quinoline guanidine derivatives with their in vitro and in vivo study
por: Sidoryk, Katarzyna, et al.
Publicado: (2017)

The effects of 1,4-dimethylpyridine in metastatic prostate cancer in mice
por: Denslow, Agnieszka, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_vapu6urno2lntvud3d61r2p6kt