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Interference with Amyloid-β Nucleation by Transient Ligand Interaction

Amyloid-β peptide (Aβ) is an intrinsically disordered protein (IDP) associated with Alzheimer’s disease. The structural flexibility and aggregation propensity of Aβ pose major challenges for elucidating the interaction between Aβ monomers and ligands. All-D-peptides consisting solely of D-enantiomer...

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Detalles Bibliográficos
Autores principales:	Zhang, Tao, Loschwitz, Jennifer, Strodel, Birgit, Nagel-Steger, Luitgard, Willbold, Dieter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600523/ https://www.ncbi.nlm.nih.gov/pubmed/31195746 http://dx.doi.org/10.3390/molecules24112129

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