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Leptin-induced Trafficking of K(ATP) Channels: A Mechanism to Regulate Pancreatic β-cell Excitability and Insulin Secretion
The adipocyte hormone leptin was first recognized for its actions in the central nervous system to regulate energy homeostasis but has since been shown to have direct actions on peripheral tissues. In pancreatic β-cells leptin suppresses insulin secretion by increasing K(ATP) channel conductance, wh...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600549/ https://www.ncbi.nlm.nih.gov/pubmed/31151172 http://dx.doi.org/10.3390/ijms20112660 |