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Epigallocatechin-3-Gallate Prevents Acute Gout by Suppressing NLRP3 Inflammasome Activation and Mitochondrial DNA Synthesis
Gout is a chronic inflammatory disease evoked by the deposition of monosodium urate (MSU) crystals in joint tissues. The nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family pyrin domain containing 3 (NLRP3) inflammasome is responsible for the gout inflammatory symptoms induced...
Autores principales: | Lee, Hye Eun, Yang, Gabsik, Park, Youn Bum, Kang, Han Chang, Cho, Yong-Yeon, Lee, Hye Suk, Lee, Joo Young |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600669/ https://www.ncbi.nlm.nih.gov/pubmed/31174271 http://dx.doi.org/10.3390/molecules24112138 |
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