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Overview of systematic reviews with meta-analyses on acupuncture in post-stroke cognitive impairment and depression management
BACKGROUND: Acupuncture has been using as an alternative non-pharmacological therapy in the management of post stroke depression and cognitive impairment but its effectiveness and safety remain controversial. We conducted an overview of systematic reviews with meta-analyses to evaluate the evidence...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600770/ https://www.ncbi.nlm.nih.gov/pubmed/31304087 http://dx.doi.org/10.1016/j.imr.2019.05.001 |
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author | Hung, Caroline Yik-fong Wu, Xin-yin Chung, Vincent Chi-ho Tang, Endy Chun-hung Wu, Justin Che-yuen Lau, Alexander Yuk-lun |
author_facet | Hung, Caroline Yik-fong Wu, Xin-yin Chung, Vincent Chi-ho Tang, Endy Chun-hung Wu, Justin Che-yuen Lau, Alexander Yuk-lun |
author_sort | Hung, Caroline Yik-fong |
collection | PubMed |
description | BACKGROUND: Acupuncture has been using as an alternative non-pharmacological therapy in the management of post stroke depression and cognitive impairment but its effectiveness and safety remain controversial. We conducted an overview of systematic reviews with meta-analyses to evaluate the evidence on the effect of acupuncture in the treatment of stroke with conventional medicine intervention. METHODS: Systematic reviews summarized the treatment effects of acupuncture for post stroke cognitive impairment and post stroke depression were considered eligible. Methodological quality of included systematic reviews was assessed using A MeaSurement Tool to Assess systematic Reviews 2 (AMSTAR 2). RESULTS: Four systematic reviews on post stroke cognitive impairment and ten systematic reviews on post stroke depression with good methodological quality were included. Meta-analyses revealed that acupuncture plus cognitive rehabilitation; and acupuncture or moxibustion plus cognitive rehabilitation, versus cognitive rehabilitation demonstrated statistically significant increase in Mini-Mental State Examination scores in compared to cognitive rehabilitation after 4 weeks treatment [Pooled weighted mean difference (WMD) = 3.14, 95% confidence interval (CI) = 2.06 to 4.21, I2 = 36%]; and (Pooled WMD = 3.22, 95% CI = 2.09 to 4.34, I2 = 0%). Furthermore, acupuncture versus antidepressant demonstrated statistically significant improve depression measured by increasing in 17-item Hamilton Depression Rating Scale in comparing to cognitive rehabilitation after 2 weeks treatment (Pooled WMD= -2.34, 95% CI= -3.46 to -1.22, I2 = 5%). Acupuncture usage was not associated with increased risk of adverse events. CONCLUSIONS: Acupuncture is safe and improves cognitive function and depressive disorder without obvious serious adverse events for post stroke patients. |
format | Online Article Text |
id | pubmed-6600770 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-66007702019-07-12 Overview of systematic reviews with meta-analyses on acupuncture in post-stroke cognitive impairment and depression management Hung, Caroline Yik-fong Wu, Xin-yin Chung, Vincent Chi-ho Tang, Endy Chun-hung Wu, Justin Che-yuen Lau, Alexander Yuk-lun Integr Med Res Review Article BACKGROUND: Acupuncture has been using as an alternative non-pharmacological therapy in the management of post stroke depression and cognitive impairment but its effectiveness and safety remain controversial. We conducted an overview of systematic reviews with meta-analyses to evaluate the evidence on the effect of acupuncture in the treatment of stroke with conventional medicine intervention. METHODS: Systematic reviews summarized the treatment effects of acupuncture for post stroke cognitive impairment and post stroke depression were considered eligible. Methodological quality of included systematic reviews was assessed using A MeaSurement Tool to Assess systematic Reviews 2 (AMSTAR 2). RESULTS: Four systematic reviews on post stroke cognitive impairment and ten systematic reviews on post stroke depression with good methodological quality were included. Meta-analyses revealed that acupuncture plus cognitive rehabilitation; and acupuncture or moxibustion plus cognitive rehabilitation, versus cognitive rehabilitation demonstrated statistically significant increase in Mini-Mental State Examination scores in compared to cognitive rehabilitation after 4 weeks treatment [Pooled weighted mean difference (WMD) = 3.14, 95% confidence interval (CI) = 2.06 to 4.21, I2 = 36%]; and (Pooled WMD = 3.22, 95% CI = 2.09 to 4.34, I2 = 0%). Furthermore, acupuncture versus antidepressant demonstrated statistically significant improve depression measured by increasing in 17-item Hamilton Depression Rating Scale in comparing to cognitive rehabilitation after 2 weeks treatment (Pooled WMD= -2.34, 95% CI= -3.46 to -1.22, I2 = 5%). Acupuncture usage was not associated with increased risk of adverse events. CONCLUSIONS: Acupuncture is safe and improves cognitive function and depressive disorder without obvious serious adverse events for post stroke patients. Elsevier 2019-09 2019-05-15 /pmc/articles/PMC6600770/ /pubmed/31304087 http://dx.doi.org/10.1016/j.imr.2019.05.001 Text en © 2019 Korea Institute of Oriental Medicine. Published by Elsevier. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Hung, Caroline Yik-fong Wu, Xin-yin Chung, Vincent Chi-ho Tang, Endy Chun-hung Wu, Justin Che-yuen Lau, Alexander Yuk-lun Overview of systematic reviews with meta-analyses on acupuncture in post-stroke cognitive impairment and depression management |
title | Overview of systematic reviews with meta-analyses on acupuncture in post-stroke cognitive impairment and depression management |
title_full | Overview of systematic reviews with meta-analyses on acupuncture in post-stroke cognitive impairment and depression management |
title_fullStr | Overview of systematic reviews with meta-analyses on acupuncture in post-stroke cognitive impairment and depression management |
title_full_unstemmed | Overview of systematic reviews with meta-analyses on acupuncture in post-stroke cognitive impairment and depression management |
title_short | Overview of systematic reviews with meta-analyses on acupuncture in post-stroke cognitive impairment and depression management |
title_sort | overview of systematic reviews with meta-analyses on acupuncture in post-stroke cognitive impairment and depression management |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600770/ https://www.ncbi.nlm.nih.gov/pubmed/31304087 http://dx.doi.org/10.1016/j.imr.2019.05.001 |
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