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Preclinical Pharmacokinetic and Safety Studies of Copper-Diacetyl-Bis(N(4)-Methylthiosemicarbazone) (Cu-ATSM): Translational Studies for Internal Radiotherapy

Hypoxia plays important roles in the prognosis of malignant brain tumors such as glioblastoma because it causes drug delivery deficiencies and the induction of hypoxia-inducible factor-1α in tumor cells. Extensive hypoxic areas are associated with poor prognosis of these fatal diseases. We previousl...

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Detalles Bibliográficos
Autores principales:	Matsumoto, Hiroki, Yoshii, Yukie, Baden, Atsumi, Kaneko, Emi, Hashimoto, Hiroki, Suzuki, Hisashi, Kawamura, Kazunori, Zhang, Ming-Rong, Higashi, Tatsuya, Kurihara, Hiroaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2019
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600784/ https://www.ncbi.nlm.nih.gov/pubmed/31252311 http://dx.doi.org/10.1016/j.tranon.2019.05.017

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