Cargando…

Endothelial cell Piezo1 mediates pressure-induced lung vascular hyperpermeability via disruption of adherens junctions

Increased pulmonary microvessel pressure experienced in left heart failure, head trauma, or high altitude can lead to endothelial barrier disruption referred to as capillary “stress failure” that causes leakage of protein-rich plasma and pulmonary edema. However, little is known about vascular endot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Friedrich, Emily E., Hong, Zhigang, Xiong, Shiqin, Zhong, Ming, Di, Anke, Rehman, Jalees, Komarova, Yulia A., Malik, Asrar B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2019
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600969/ https://www.ncbi.nlm.nih.gov/pubmed/31186359 http://dx.doi.org/10.1073/pnas.1902165116

Ejemplares similares

Mechanosensing Piezo channels in tissue homeostasis including their role in lungs
por: Zhong, Ming, et al.
Publicado: (2018)

N-cadherin signaling via Trio assembles adherens junctions to restrict endothelial permeability
por: Kruse, Kevin, et al.
Publicado: (2019)

Excess centrosomes disrupt vascular lumenization and endothelial cell adherens junctions
por: Buglak, Danielle B., et al.
Publicado: (2020)

Tension across adherens junctions: when less is more
por: Kruse, Kevin, et al.
Publicado: (2015)

Ubiquitin ligase CHFR mediated degradation of VE-cadherin through ubiquitylation disrupts endothelial adherens junctions
por: Tiruppathi, Chinnaswamy, et al.
Publicado: (2023)

Sox17 is required for endothelial regeneration following inflammation-induced vascular injury
por: Liu, Menglin, et al.
Publicado: (2019)

Evidence of a common mechanism of disassembly of adherens junctions through Gα13 targeting of VE-cadherin
por: Gong, Haixia, et al.
Publicado: (2014)

Mitofusin-2 stabilizes adherens junctions and suppresses endothelial inflammation via modulation of β-catenin signaling
por: Kim, Young-Mee, et al.
Publicado: (2021)

Disruption of endothelial adherens junctions by high glucose is mediated by protein kinase C-β–dependent vascular endothelial cadherin tyrosine phosphorylation
por: Haidari, Mehran, et al.
Publicado: (2014)

Disruption of endothelial adherens junctions by high glucose is mediated by protein kinase C-β–dependent vascular endothelial cadherin tyrosine phosphorylation
por: Haidari, Mehran, et al.
Publicado: (2014)

Regulation of Endothelial Adherens Junctions by Tyrosine Phosphorylation
por: Adam, Alejandro Pablo
Publicado: (2015)

CCL2 Disrupts the Adherens Junction: Implications for Neuroinflammation
por: Roberts, Toni K., et al.
Publicado: (2012)

Histamine Induces Vascular Hyperpermeability by Increasing Blood Flow and Endothelial Barrier Disruption In Vivo
por: Ashina, Kohei, et al.
Publicado: (2015)

Endothelial heterogeneity across distinct vascular beds during homeostasis and inflammation
por: Jambusaria, Ankit, et al.
Publicado: (2020)

Correction to: Disruption of endothelial adherens junctions by high glucose is mediated by protein kinase C-β–dependent vascular endothelial cadherin tyrosine phosphorylation
por: Haidari, Mehran, et al.
Publicado: (2017)

Histone Demethylases KDM4A and KDM4C Regulate Differentiation of Embryonic Stem Cells to Endothelial Cells
por: Wu, Liangtang, et al.
Publicado: (2015)

Interleukin-1RA Mitigates SARS-CoV-2–Induced Inflammatory Lung Vascular Leakage and Mortality in Humanized K18-hACE-2 Mice
por: Xiong, Shiqin, et al.
Publicado: (2021)

Endothelial adherens junctions and the actin cytoskeleton: an 'infinity net'?
por: Lampugnani, Maria Grazia
Publicado: (2010)

Piezo2 protein: A novel regulator of tumor angiogenesis and hyperpermeability
por: Yang, Hong, et al.
Publicado: (2016)

WIF1 prevents Wnt5A mediated LIMK/CFL phosphorylation and adherens junction disruption in human vascular endothelial cells
por: Skaria, Tom, et al.
Publicado: (2017)

Piezo1 induces endothelial responses to shear stress via soluble adenylyl Cyclase-IP(3)R2 circuit
por: Santana Nunez, Dianicha, et al.
Publicado: (2023)

FoxM1 regulates re-annealing of endothelial adherens junctions through transcriptional control of β-catenin expression
por: Mirza, Muhammad K., et al.
Publicado: (2010)

Formin' adherens junctions
por: Wells, William A.
Publicado: (2004)

Virtual adherens junctions
por: Wells, William A.
Publicado: (2006)

Method for Dual Viral Vector Mediated CRISPR-Cas9 Gene Disruption in Primary Human Endothelial Cells
por: Gong, Haixia, et al.
Publicado: (2017)

YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development
por: Neto, Filipa, et al.
Publicado: (2018)

Dengue Virus NS1 Disrupts the Endothelial Glycocalyx, Leading to Hyperpermeability
por: Puerta-Guardo, Henry, et al.
Publicado: (2016)

Mechanisms of Mechanical Force Induced Pulmonary Vascular Endothelial Hyperpermeability
por: Lai, Yan, et al.
Publicado: (2021)

Exposure to Zinc Oxide Nanoparticles Disrupts Endothelial Tight and Adherens Junctions and Induces Pulmonary Inflammatory Cell Infiltration
por: Chen, Chen-Mei, et al.
Publicado: (2020)

Circulating extracellular vesicles from patients with acute chest syndrome disrupt adherens junctions between endothelial cells
por: Lapping-Carr, Gabrielle, et al.
Publicado: (2020)

Molecular heterogeneity of adherens junctions
Publicado: (1985)

Adherens junctions remain dynamic
por: Falk, Matthias M
Publicado: (2010)

Vascular permeability, vascular hyperpermeability and angiogenesis
por: Nagy, Janice A., et al.
Publicado: (2008)

Adherens junctions connect stress fibres between adjacent endothelial cells
por: Millán, Jaime, et al.
Publicado: (2010)

A Labile Pool of IQGAP1 Disassembles Endothelial Adherens Junctions
por: Yuan, Zhiguo, et al.
Publicado: (2013)

Kaposi's sarcoma-associated herpes virus disrupts adherens junctions and increases endothelial permeability by inducing degradation of VE-cadherin
por: Qian, LW, et al.
Publicado: (2009)

Histamine causes endothelial barrier disruption via Ca(2+)-mediated RhoA activation and tension at adherens junctions
por: Kugelmann, Daniela, et al.
Publicado: (2018)

Ve-ptp Modulates Vascular Integrity by Promoting Adherens Junction Maturation
por: Carra, Silvia, et al.
Publicado: (2012)

Endothelial cell SMAD6 balances Alk1 function to regulate adherens junctions and hepatic vascular development
por: Kulikauskas, Molly R., et al.
Publicado: (2023)

VE-PTP stabilizes VE-cadherin junctions and the endothelial barrier via a phosphatase-independent mechanism
por: Juettner, Vanessa V., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_oqppnjj1eia4p2uej0ndcvr3li