NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms

Ncoa4 mediates autophagic degradation of ferritin, the cytosolic iron storage complex, to maintain intracellular iron homeostasis. Recent evidence also supports a role for Ncoa4 in systemic iron homeostasis and erythropoiesis. However, the specific contribution and temporal importance of Ncoa4-media...

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Detalles Bibliográficos
Autores principales: Santana-Codina, Naiara, Gableske, Sebastian, del Rey, Maria Quiles, Małachowska, Beata, Jedrychowski, Mark P., Biancur, Douglas E., Schmidt, Paul J., Fleming, Mark D., Fendler, Wojciech, Harper, J. Wade, Kimmelman, Alec C., Mancias, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601094/
https://www.ncbi.nlm.nih.gov/pubmed/30630985
http://dx.doi.org/10.3324/haematol.2018.204123

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