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Gradient-dependent inhibition of stimulatory signaling from platelet G protein-coupled receptors

As platelet activation is an irreversible and potentially harmful event, platelet stimulatory signaling must be tightly regulated to ensure the filtering-out of inconsequential fluctuations of agonist concentrations in the vascular milieu. Herein, we show that platelet activation via G protein-coupl...

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Detalles Bibliográficos
Autores principales: Macwan, Ankit S., Boknäs, Niklas, Ntzouni, Maria P., Ramström, Sofia, Gibbins, Jonathan M., Faxälv, Lars, Lindahl, Tomas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601095/
https://www.ncbi.nlm.nih.gov/pubmed/30630981
http://dx.doi.org/10.3324/haematol.2018.205815