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Gradient-dependent inhibition of stimulatory signaling from platelet G protein-coupled receptors
As platelet activation is an irreversible and potentially harmful event, platelet stimulatory signaling must be tightly regulated to ensure the filtering-out of inconsequential fluctuations of agonist concentrations in the vascular milieu. Herein, we show that platelet activation via G protein-coupl...
Autores principales: | Macwan, Ankit S., Boknäs, Niklas, Ntzouni, Maria P., Ramström, Sofia, Gibbins, Jonathan M., Faxälv, Lars, Lindahl, Tomas L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601095/ https://www.ncbi.nlm.nih.gov/pubmed/30630981 http://dx.doi.org/10.3324/haematol.2018.205815 |
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