Cargando…

Targeting BCL2 with venetoclax is a promising therapeutic strategy for “double-proteinexpression” lymphoma with MYC and BCL2 rearrangements

The so-called “double-hit” and “double-protein-expression” lymphoma with MYC and BCL2 rearrangements is a rare, mature B-cell neoplasm characterized by a germinal center B-cell phenotype, abundant protein expression of MYC and BCL2, rapid disease progression, and a poor prognosis. In this study, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Uchida, Akiko, Isobe, Yasushi, Asano, Junko, Uemura, Yu, Hoshikawa, Masahiro, Takagi, Masayuki, Miura, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601100/
https://www.ncbi.nlm.nih.gov/pubmed/30523053
http://dx.doi.org/10.3324/haematol.2018.204958