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Targeting BCL2 with venetoclax is a promising therapeutic strategy for “double-proteinexpression” lymphoma with MYC and BCL2 rearrangements
The so-called “double-hit” and “double-protein-expression” lymphoma with MYC and BCL2 rearrangements is a rare, mature B-cell neoplasm characterized by a germinal center B-cell phenotype, abundant protein expression of MYC and BCL2, rapid disease progression, and a poor prognosis. In this study, we...
Autores principales: | Uchida, Akiko, Isobe, Yasushi, Asano, Junko, Uemura, Yu, Hoshikawa, Masahiro, Takagi, Masayuki, Miura, Ikuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601100/ https://www.ncbi.nlm.nih.gov/pubmed/30523053 http://dx.doi.org/10.3324/haematol.2018.204958 |
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