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FGFR(3S249C) mutation promotes chemoresistance by activating Akt signaling in bladder cancer cells

Fibroblast growth factor receptor 3 (FGFR3) is a high frequency mutant gene in bladder cancer (BCa) and has become a promising therapeutic target due to its involvement in cell proliferation and migration. However, whether and how FGFR3 mutations affects BCa cell chemosensitivity is unknown. The cur...

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Detalles Bibliográficos
Autores principales:	Xie, Xina, Lin, Jiatian, Zhong, Yuantang, Fu, Mianheng, Tang, Aifa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601368/ https://www.ncbi.nlm.nih.gov/pubmed/31316618 http://dx.doi.org/10.3892/etm.2019.7672

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