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Deficient IL‐6/Stat3 Signaling, High TLR7, and Type I Interferons in Early Human Alcoholic Liver Disease: A Triad for Liver Damage and Fibrosis

Mechanisms underlying alcohol‐induced liver injury and its progression still remain incompletely understood. Animal models can only address some aspects of the pathophysiology that requires studies directly in humans, which are scarce. We assessed liver inflammatory and immune responses at early sta...

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Detalles Bibliográficos
Autores principales: Stärkel, Peter, Schnabl, Bernd, Leclercq, Sophie, Komuta, Mina, Bataller, Ramon, Argemi, Josepmaria, Palma, Elena, Chokshi, Shilpa, Hellerbrand, Claus, Maccioni, Luca, Lanthier, Nicolas, Leclercq, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601428/
https://www.ncbi.nlm.nih.gov/pubmed/31334440
http://dx.doi.org/10.1002/hep4.1364