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Deficient IL‐6/Stat3 Signaling, High TLR7, and Type I Interferons in Early Human Alcoholic Liver Disease: A Triad for Liver Damage and Fibrosis
Mechanisms underlying alcohol‐induced liver injury and its progression still remain incompletely understood. Animal models can only address some aspects of the pathophysiology that requires studies directly in humans, which are scarce. We assessed liver inflammatory and immune responses at early sta...
Autores principales: | Stärkel, Peter, Schnabl, Bernd, Leclercq, Sophie, Komuta, Mina, Bataller, Ramon, Argemi, Josepmaria, Palma, Elena, Chokshi, Shilpa, Hellerbrand, Claus, Maccioni, Luca, Lanthier, Nicolas, Leclercq, Isabelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601428/ https://www.ncbi.nlm.nih.gov/pubmed/31334440 http://dx.doi.org/10.1002/hep4.1364 |
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