Cargando…

Tongxinluo Attenuates Myocardiac Fibrosis after Acute Myocardial Infarction in Rats via Inhibition of Endothelial-to-Mesenchymal Transition

Endothelial-to-mesenchymal transition (EndMT) is an essential mechanism in myocardial fibrosis (MF). Tongxinluo (TXL) has been confirmed to protect the endothelium against reperfusion injury after acute myocardial infarction (AMI). However, whether TXL can inhibit MF after AMI via inhibiting EndMT r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yin, Yujie, Zhang, Qian, Zhao, Qifei, Ding, Guoyuan, Wei, Cong, Chang, Liping, Li, Hongrong, Bei, Hongying, Wang, Hongtao, Liang, Junqing, Jia, Zhenhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601481/ https://www.ncbi.nlm.nih.gov/pubmed/31317035 http://dx.doi.org/10.1155/2019/6595437

Ejemplares similares

Tongxinluo Regulates Expression of Tight Junction Proteins and Alleviates Endothelial Cell Monolayer Hyperpermeability via ERK-1/2 Signaling Pathway in Oxidized Low-Density Lipoprotein-Induced Human Umbilical Vein Endothelial Cells
por: Chang, Chengcheng, et al.
Publicado: (2017)

LncRNA MALAT1 modulates ox-LDL induced EndMT through the Wnt/β-catenin signaling pathway
por: Li, Hongrong, et al.
Publicado: (2019)

Lactate and Myocardiac Energy Metabolism
por: Dong, Shuohui, et al.
Publicado: (2021)

Tongxinluo enhances the effect of atorvastatin on the treatment of atherosclerosis with chronic obstructive pulmonary disease by maintaining the pulmonary microvascular barrier
por: Kuang, Xiangnan, et al.
Publicado: (2022)

Corrigendum: Lactate and Myocardiac Energy Metabolism
por: Dong, Shuohui, et al.
Publicado: (2022)

Willingness to pay for health care services in common cold, retinal detachment, and myocardiac infarction: an internet survey in Japan
por: Yasunaga, Hideo, et al.
Publicado: (2006)

Tongxinluo Improves Cardiac Function and Ameliorates Ventricular Remodeling in Mice Model of Myocardial Infarction through Enhancing Angiogenesis
por: Bai, Wen-Wu, et al.
Publicado: (2013)

Tongxinluo promotes endothelium-dependent arteriogenesis to attenuate diabetic peripheral arterial disease
por: Gu, Jiao-Jiao, et al.
Publicado: (2023)

Tongxinluo Reverses the Hypoxia-suppressed Claudin-9 in Cardiac Microvascular Endothelial Cells
por: Liu, Kun, et al.
Publicado: (2016)

Tongxinluo Prevents Endothelial Dysfunction Induced by Homocysteine Thiolactone In Vivo via Suppression of Oxidative Stress
por: Zhang, Yi, et al.
Publicado: (2015)

Cardiac Microvascular Barrier Function Mediates the Protection of Tongxinluo against Myocardial Ischemia/Reperfusion Injury
por: Qi, Kang, et al.
Publicado: (2015)

Tongxinluo attenuates reperfusion injury in diabetic hearts by angiopoietin-like 4-mediated protection of endothelial barrier integrity via PPAR-α pathway
por: Qi, Kang, et al.
Publicado: (2018)

A Comparative Study of Embedded and Anesthetized Zebrafish in vivo on Myocardiac Calcium Oscillation and Heart Muscle Contraction
por: Muntean, Brian S., et al.
Publicado: (2010)

Pigment epithelium-derived factor attenuates myocardial fibrosis via inhibiting Endothelial-to-Mesenchymal Transition in rats with acute myocardial infarction
por: Zhang, Hao, et al.
Publicado: (2017)

China Tongxinluo Study for myocardial protection in patients with Acute Myocardial Infarction (CTS-AMI): Rationale and design of a randomized, double-blind, placebo-controlled, multicenter clinical trial
por: Xu, Yi, et al.
Publicado: (2020)

Tongxinluo Improves Apolipoprotein E-Deficient Mouse Heart Function
por: Yuan, Guo-Qiang, et al.
Publicado: (2018)

Tongxinluo promotes axonal plasticity and functional recovery after stroke
por: Wang, Xiaoting, et al.
Publicado: (2020)

Corosolic acid attenuates cardiac fibrosis following myocardial infarction in mice
por: Wang, Zhao-Peng, et al.
Publicado: (2020)

Potential Effectiveness of Chinese Patent Medicine Tongxinluo Capsule for Secondary Prevention After Acute Myocardial Infarction: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
por: Li, Min, et al.
Publicado: (2018)

Effect of Tongxinluo on Nephrin Expression via Inhibition of Notch1/Snail Pathway in Diabetic Rats
por: Cui, Fangqiang, et al.
Publicado: (2015)

Traditional Chinese Medication Tongxinluo Attenuates Lipidosis in Ox-LDL-Stimulated Macrophages by Enhancing Beclin-1-Induced Autophagy
por: Chen, Yifei, et al.
Publicado: (2021)

Tongxinluo Enhances Neurogenesis and Angiogenesis in Peri-Infarct Area and Subventricular Zone and Promotes Functional Recovery after Focal Cerebral Ischemic Infarction in Hypertensive Rats
por: Chen, Li, et al.
Publicado: (2016)

The ACE2-Ang (1–7)-Mas receptor axis attenuates cardiac remodeling and fibrosis in post-myocardial infarction
por: Wang, Juan, et al.
Publicado: (2017)

Tongxinluo (TXL), a Traditional Chinese Medicinal Compound, Improves Endothelial Function After Chronic Hypoxia Both In Vivo and In Vitro
por: Zheng, Cui-Ying, et al.
Publicado: (2015)

Inhibiting leukocyte‐endothelial cell interactions by Chinese medicine Tongxinluo capsule alleviates no‐reflow after arterial recanalization in ischemic stroke
por: Liu, Shen, et al.
Publicado: (2023)

The mechanism of miR-142-3p in coronary microembolization-induced myocardiac injury via regulating target gene IRAK-1
por: Su, Qiang, et al.
Publicado: (2019)

Dihydrolycorine Attenuates Cardiac Fibrosis and Dysfunction by Downregulating Runx1 following Myocardial Infarction
por: Ni, Tingjuan, et al.
Publicado: (2021)

Traditional Chinese Medicine Tongxinluo Improves Cardiac Function of Rats with Dilated Cardiomyopathy
por: Shen, Fang-Fang, et al.
Publicado: (2014)

Correction to: The mechanism of miR-142-3p in coronary microembolization-induced myocardiac injury via regulating target gene IRAK-1
por: Su, Qiang, et al.
Publicado: (2022)

miR-30a attenuates cardiac fibrosis in rats with myocardial infarction by inhibiting CTGF
por: Chen, Liwen, et al.
Publicado: (2018)

MicroRNA-132 attenuated cardiac fibrosis in myocardial infarction-induced heart failure rats
por: Wang, Guoyu, et al.
Publicado: (2020)

Systematic Review of Tongxinluo Capsule on the Therapeutic Effect and Hemorheology of Patients with Transient Ischemic Attack
por: Yang, Peng, et al.
Publicado: (2021)

Tongxinluo May Alleviate Inflammation and Improve the Stability of Atherosclerotic Plaques by Changing the Intestinal Flora
por: Qi, Yan, et al.
Publicado: (2022)

Beraprost sodium attenuates the development of myocardial fibrosis after myocardial infarction by regulating GSK‐3β expression in rats
por: Li, Xing‐Xing, et al.
Publicado: (2023)

Tongxinluo attenuates oxygen-glucose-serum deprivation/restoration-induced endothelial barrier breakdown via peroxisome proliferator activated receptor-α/angiopoietin-like 4 pathway in high glucose-incubated human cardiac microvascular endothelial cells
por: Qi, Kang, et al.
Publicado: (2020)

The role and mechanism of transforming growth factor beta 3 in human myocardial infarction‐induced myocardial fibrosis
por: Xue, Ke, et al.
Publicado: (2019)

Aging Attenuates Cardiac Contractility and Affects Therapeutic Consequences for Myocardial Infarction
por: Dong, Ming, et al.
Publicado: (2020)

Chinese Patent Medicine Tongxinluo Capsule for Hypertension: A Systematic Review of Randomised Controlled Trials
por: Wang, Jie, et al.
Publicado: (2014)

Neuroprotective effect of the traditional Chinese herbal formula Tongxinluo: a PET imaging study in rats
por: Cheng, Xiao, et al.
Publicado: (2014)

PGC-1α Mediated Peripheral Nerve Protection of Tongxinluo in STZ-Induced Diabetic Rats
por: Cui, Xiaopei, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_4u039ljmlkqdlh3e1f624ibh4q