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Phase separation of Polycomb-repressive complex 1 is governed by a charged disordered region of CBX2

Mammalian development requires effective mechanisms to repress genes whose expression would generate inappropriately specified cells. The Polycomb-repressive complex 1 (PRC1) family complexes are central to maintaining this repression. These include a set of canonical PRC1 complexes, each of which c...

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Detalles Bibliográficos
Autores principales:	Plys, Aaron J., Davis, Christopher P., Kim, Jongmin, Rizki, Gizem, Keenen, Madeline M., Marr, Sharon K., Kingston, Robert E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601514/ https://www.ncbi.nlm.nih.gov/pubmed/31171700 http://dx.doi.org/10.1101/gad.326488.119

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