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Fast protein sequencing of monoclonal antibody by real-time digestion on emitter during nanoelectrospray
Growth in the pharmaceutical industry has led to an increasing demand for rapid characterization of therapeutic monoclonal antibodies. The current methods for antibody sequence confirmation (e.g., N-terminal Edman sequencing and traditional peptide mapping methods) are not sufficient; thus, we devel...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601538/ https://www.ncbi.nlm.nih.gov/pubmed/30919719 http://dx.doi.org/10.1080/19420862.2019.1599633 |