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Combining the best of two worlds: highly flexible chimeric antigen receptor adaptor molecules (CAR-adaptors) for the recruitment of chimeric antigen receptor T cells

Chimeric antigen receptor (CAR)-engineered T cells have a proven efficacy for the treatment of refractory hematological B cell malignancies. While often accompanied by side effects, CAR-T technology is getting more mature and will become an important treatment option for various tumor indications. I...

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Detalles Bibliográficos
Autores principales: Darowski, Diana, Kobold, Sebastian, Jost, Christian, Klein, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601549/
https://www.ncbi.nlm.nih.gov/pubmed/30892136
http://dx.doi.org/10.1080/19420862.2019.1596511