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Neonatal Fc receptor expression in macrophages is indispensable for IgG homeostasis
The maintenance of the homeostasis of immunoglobulin G (IgG) represents a fundamental aspect of humoral immunity that has direct relevance to the successful delivery of antibody-based therapeutics. The ubiquitously expressed neonatal Fc receptor (FcRn) salvages IgG from cellular degradation followin...
Autores principales: | Challa, Dilip K., Wang, Xiaoli, Montoyo, Héctor Pérez, Velmurugan, Ramraj, Ober, Raimund J., Ward, E. Sally |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601554/ https://www.ncbi.nlm.nih.gov/pubmed/30964743 http://dx.doi.org/10.1080/19420862.2019.1602459 |
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