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Neonatal Fc receptor expression in macrophages is indispensable for IgG homeostasis

The maintenance of the homeostasis of immunoglobulin G (IgG) represents a fundamental aspect of humoral immunity that has direct relevance to the successful delivery of antibody-based therapeutics. The ubiquitously expressed neonatal Fc receptor (FcRn) salvages IgG from cellular degradation followin...

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Detalles Bibliográficos
Autores principales: Challa, Dilip K., Wang, Xiaoli, Montoyo, Héctor Pérez, Velmurugan, Ramraj, Ober, Raimund J., Ward, E. Sally
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601554/
https://www.ncbi.nlm.nih.gov/pubmed/30964743
http://dx.doi.org/10.1080/19420862.2019.1602459

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