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A comprehensive search of functional sequence space using large mammalian display libraries created by gene editing
The construction of large libraries in mammalian cells allows the direct screening of millions of molecular variants for binding properties in a cell type relevant for screening or production. We have created mammalian cell libraries of up to 10 million clones displaying a repertoire of IgG-formatte...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601556/ https://www.ncbi.nlm.nih.gov/pubmed/31107136 http://dx.doi.org/10.1080/19420862.2019.1618673 |