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Genetic variants in p53 signaling pathway genes predict chemotherapy efficacy in colorectal cancer

BACKGROUND: The murine double minute‐2 gene (MDM2) was originally identified as predicting chemotherapy efficacy. However, little is known regarding the association between single nucleotide polymorphisms (SNPs) in the p53 signaling pathway and prognosis/chemotherapy sensitivity in colorectal cancer...

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Detalles Bibliográficos
Autores principales:	Zhang, Ke, Meng, Yixuan, Cao, Xiangming, Xu, Ye, Du, Mulong, Wu, Yuan, Liu, Lingxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Clinical Cancer Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601596/ https://www.ncbi.nlm.nih.gov/pubmed/31090204 http://dx.doi.org/10.1002/cam4.2215

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