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Combination Therapy with a PI3K/mTOR Dual Inhibitor and Chloroquine Enhances Synergistic Apoptotic Cell Death in Epstein–Barr Virus-Infected Gastric Cancer Cells

The phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) signaling pathway is a promising target for gastric cancer (GC) treatment; however the efficacy of PI3K/mTOR dual inhibitors in GC has not yet been maximized. Additionally, the effect of autophagy regulation...

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Detalles Bibliográficos
Autores principales:	Kim, Mi-Young, Kruger, Annie J., Jeong, Ju-Yeon, Kim, Jaehee, Shin, Phil kyung, Kim, Sun Young, Cho, Joo Young, Hahm, Ki Baik, Hong, Sung Pyo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602147/ https://www.ncbi.nlm.nih.gov/pubmed/31085812 http://dx.doi.org/10.14348/molcells.2019.2395

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