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LL-37 alone and in combination with IL17A enhances proinflammatory cytokine expression in parallel with hyaluronan metabolism in human synovial sarcoma cell line SW982—A step toward understanding the development of inflammatory arthritis
LL-37 is the only human cathelicidin-family host defense peptide and has been reported to interact with invading pathogens causing inflammation at various body sites. Recent studies showed high levels of LL-37 in the synovial-lining membrane of patients with rheumatoid arthritis, a common type of in...
Autores principales: | Kuensaen, Chakkrapong, Chomdej, Siriwadee, Kongdang, Patiwat, Sirikaew, Nutnicha, Jaitham, Rungnaree, Thonghoi, Supitcha, Ongchai, Siriwan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602187/ https://www.ncbi.nlm.nih.gov/pubmed/31260471 http://dx.doi.org/10.1371/journal.pone.0218736 |
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