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Anterior cleft palate due to Cbfb deficiency and its rescue by folic acid

Core binding factor β (Cbfb) is a cofactor of the Runx family of transcription factors. Among these transcription factors, Runx1 is a prerequisite for anterior-specific palatal fusion. It was previously unclear, however, whether Cbfb served as a modulator or as an obligatory factor in the Runx signa...

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Detalles Bibliográficos
Autores principales: Sarper, Safiye E., Inubushi, Toshihiro, Kurosaka, Hiroshi, Ono Minagi, Hitomi, Murata, Yuka, Kuremoto, Koh-ichi, Sakai, Takayoshi, Taniuchi, Ichiro, Yamashiro, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602316/
https://www.ncbi.nlm.nih.gov/pubmed/31171577
http://dx.doi.org/10.1242/dmm.038851