Lgr5(+) stem and progenitor cells reside at the apex of a heterogeneous embryonic hepatoblast pool

During mouse embryogenesis, progenitors within the liver known as hepatoblasts give rise to adult hepatocytes and cholangiocytes. Hepatoblasts, which are specified at E8.5-E9.0, have been regarded as a homogeneous progenitor population that initiate differentiation from E13.5. Recently, scRNA-seq an...

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Detalles Bibliográficos
Autores principales: Prior, Nicole, Hindley, Christopher J., Rost, Fabian, Meléndez, Elena, Lau, Winnie W. Y., Göttgens, Berthold, Rulands, Steffen, Simons, Benjamin D., Huch, Meritxell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Stem Cells and Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602348/
https://www.ncbi.nlm.nih.gov/pubmed/31142540
http://dx.doi.org/10.1242/dev.174557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602348/
https://www.ncbi.nlm.nih.gov/pubmed/31142540
http://dx.doi.org/10.1242/dev.174557

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