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mCSM-PPI2: predicting the effects of mutations on protein–protein interactions
Protein–protein Interactions are involved in most fundamental biological processes, with disease causing mutations enriched at their interfaces. Here we present mCSM-PPI2, a novel machine learning computational tool designed to more accurately predict the effects of missense mutations on protein–pro...
Autores principales: | Rodrigues, Carlos H M, Myung, Yoochan, Pires, Douglas E V, Ascher, David B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602427/ https://www.ncbi.nlm.nih.gov/pubmed/31114883 http://dx.doi.org/10.1093/nar/gkz383 |
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